Our Research
Applying Science to Help People Proactively Improve Wellness
Phenomune is constantly working to proactively research, discover, and find solutions to help provide insight and improve the wellness of our customers. Through ongoing research led by our Founder and Chief Medical and Scientific Officer, Dr. Henry Barham, Phenomune works to meet and maintain high standards of accuracy, usability and reliability of our products. Driven by a desire to provide easy-to-use at-home methods to carefully and optimally deliver personalized information and education to customers, Phenomune is dedicated to continuous learning and building scientific evidence to improve the utility of our products to help empower and engage our customers on their quest for wellness.
Dr. Barham is regularly involved in clinical trials and has authored over 100 publications and book chapters on various medical topics. He is a board-certified ear, nose, and throat (ENT) physician who completed a rhinology fellowship (nose, sinus, allergy, endoscopic sinus, and skull base surgery). He practices at Sinus and Nasal Specialists of Louisiana, LLC and is the director of the Rhinology and Skull Base Research Group. Dr. Barham received an M.D. from Louisiana State University Health Sciences Center in Shreveport. He completed a residency in otolaryngology head and neck surgery at the University of Colorado in Denver. He went on to specialize in formal rhinology, rhinoplasty, and skull base surgery at the Sydney Rhinology Fellowship.
Dr. Barham continues his involvement in clinical research. The following are some papers authored by Dr. Barham, both related to current ongoing research and past research, including:
"Association Between Bitter Taste Receptor Phenotype and Clinical Outcomes Among Patients With COVID-19"
JAMA Netw Open. 2021
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"Treatment Protocol for COVID-19 Based on T2R Phenotype"
Viruses. Vol. 13, no. 503. 2021.
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"Does phenotypic expression of bitter taste receptor T2R38 show association with COVID‐19 severity?"
International Forum of Allergy & Rhinology. Vol. 10, no.11. 2020.
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"Nasal Endoscopy During COVID-19"
American Journal of Rhinology & Allergy. Vol. 34, no. 6. 2020.
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"Rhinologic Procedures in the Era of COVID-19: Health-care Provider Protection Protocol"
American Journal of Rhinology & Allergy. Vol. 34, no. 4. 2020.
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"Outcomes after Endoscopic Dacryocystorhinostomy in the Pediatric Population"
American Journal of Biomedical Science & Research. Vol. 7, no. 5. 2020.
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"Long-Term Sinonasal Function Following Transnasal Pituitary Surgery: A Comparison of Surgical Approach"
American Journal of Rhinology & Allergy. Vol. 34, no. 3. 2020.
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"Long-Term Outcomes After Endoscopic Dacryocystorhinostomy Without Mucosal Flap Preservation"
The Laryngoscope. Vol. 130, no. 1. 2020.
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"Impact of Draf III, Draf IIb, and Draf IIa Frontal Sinus Surgery on Nasal Irrigation Distribution"
International Forum of Allergy & Rhinology. Vol. 10, no. 1. 2019.
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"Multidisciplinary Team Care in the Surgical Management of Pituitary Adenoma"
Journal of Neurological Surgery Part B: Skull Base. 2019.
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"The Distinguishing Clinical Features of Nonallergic Rhinitis Patients"
American Journal of Rhinology & Allergy. Vol. 33, no. 5. 2019.
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"Nasal Mucosal Brushing as a Diagnostic Method for Allergic Rhinitis"
Allergy and Asthma Proceedings. Vol. 40. no. 3. 2019.
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"Voice Outcomes After Endoscopic Sinus Surgery in Patients with Chronic Rhinosinusitis with Nasal Polyposis"
The Laryngoscope. Vol. 129, no. 2. 2019.
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"Turbinate-Specific IgE in Normal and Rhinitic Patients"
American Journal of Rhinology & Allergy. Vol. 33, no. 2. 2019.
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"Total Intravenous Anesthesia Improves Intraoperative Visualization During Surgery For High-Grade Chronic Rhinosinusitis: A Double-Blind Randomized Controlled Trial"
International Forum of Allergy & Rhinology. Vol. 8, no. 10. 2018.
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"Optimizing Protein Harvest From Nasal Brushings for Determining Local Allergy Responses"
American Journal of Rhinology & Allergy. Vol. 32, no. 4. 2018.
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"Airflow and Symptom Outcomes Between Allergic and Non-Allergic Rhinitis Patients From Turbinoplasty"
Rhinology. Vol. 55, no. 4. 2017.
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"RNA Sequencing and Pathway Analysis Identify Tumor Necrosis Factor Alpha Driven Small Proline-Rich Protein Dysregulation in Chronic Rhinosinusitis"
American Journal of Rhinology & Allergy. Vol. 31, no. 5. 2017.
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"Costal Cartilage Lateral Crural Strut Graft VS Cephalic Crural Turin-in for Correction of External Valve Dysfunction"
JAMA Facial Plastic Surgery. Vol. 17, no. 5. 2017.
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"Isolated Sphenoid Sinus Opacification: A Systematic Review"
American Journal of Otolaryngology. Vol. 38, no. 2. 2017.
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"Association of Gastro-Oesophageal Reflux and Chronic Rhinosinusitis: Systematic Review and Meta-Analysis"
Rhinology. Vol. 55, no. 1. 2017.
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"Acute Radiology Rarely Confirms Sinus Disease in Suspected Recurrent Acute Rhinosinusitis"
International Forum of Allergy & Rhinology. Vol. 7, no. 7. 2017.
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"Allergic Sensitization Does Not Predispose to Sinus Inflammation in Externalized Paranasal Sinuses"
American Journal of Rhinology & Allergy. Vol. 31, no. 1. 2017.
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"Two-Dimensional Assessment of the Nasal Valve Area Cannot Predict Minimum Cross-Sectional Area or Airflow Resistance"
American Journal of Rhinology & Allergy. Vol. 30, no. 3. 2016.
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"Prognostic Factors in the Outcome of Invasive Fungal Sinusitis in a Pediatric Population"
The Pediatric Infectious Disease Journal. Vol. 35, no. 4. 2016.
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"Clinical Implications of Mucosal Remodeling from Chronic Rhinosinusitis"
International Forum of Allergy & Rhinology. Vol. 6, no. 8. 2016.
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"Frontal Sinus Surgery and Sinus Distribution of Nasal Irrigation"
International Forum of Allergy & Rhinology. Vol. 6, no. 3. 2016.
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"Using Fixed Anatomical Landmarks to Avoid Medial Rectus Injury: A Radiographic Analysis in Patients with and without Graves' Disease"
American Journal of Otolaryngology. Vol. 34, no. 4. 2016.
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"Long-Term Outcomes in Medial Flap Inferior Turbinoplasty are Superior to Submucosal Electrocautery and Submucosal Powered Turbinate Reduction"
International Forum of Allergy & Rhinology. Vol. 6, no. 2. 2016.
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"Nasal Saline Irrigation: Therapeutic or Homeopathic"
Brazilian Journal of Otorhinolaryngology. Vol. 81, no. 5. 2015.
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"Topical Concentrated Epinephrine (1:1000) Does Not Cause Acute Cardiovascular Changes During Endoscopic Sinus Surgery"
International Forum of Allergy & Rhinology. Vol. 6, no. 2. 2015.
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"Remodelling Changes of the Upper Airway with Chronic Rhinosinusitis"
International Forum of Allergy & Rhinology. Vol. 5, no. 7. 2015.
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"Sinonasal Morbidity Post Tumor Resection with and without Nasoseptal Flap Reconstruction"
Rhinology. Vol. 53, no. 2. 2015.
Link to Article
"The Olfactory Strip and Its Preservation in Endoscopic Pituitary Surgery Maintains Smell and Sinonasal Function"
Journal of Neurological Surgery Part B: Skull Base. 2015.
Link to Article
"Comparison of Radiographic and Clinical Characteristics of Low-Risk and High-Risk Cystic Fibrosis Genotypes"
International Forum of Allergy & Rhinology. Vol. 4, no. 11. 2014.
Link to Article
"Solitary Chemosensory Cells and Bitter Taste Receptor Signaling in Human Sinonasal Mucosa"
International Forum of Allergy & Rhinology. Vol. 3, no. 6. 2013.
Link to Article